Dr. Abby Dolan is the newest Emergency Room doctor at Patience Regional Hospital in the small California town of Patience. After only a few weeks on the job, she has managed to impress some with her life-saving skills, but she has also offended others in the hospital with her blunt orders. While striving to find her niche at the hospital and be accepted by the staff, Abby starts to realize that an abundance of her patients suffer from symptoms for which she cannot find a diagnosis; symptoms such as itching and headaches. She becomes frustrated when she cannot discover the reason for the patients' discomfort. And when her fiancee Josh Wyler starts having headaches and displaying uncharacteristically violent tendencies, Abby's fear and confusion are heightened.
As Abby begins to research these strange cases, she finds that Colstar, the massive battery-producing factory that gives life to Patience, seems to be a key player for each patient. The more she delves into her research, the more curious findings come to light. When a violent car accident that was intended to be a murder-suicide occurs, and the culprit is a Colstar employee, Abby becomes sure Colstar is responsible for all the cases - caused by Cadmium poisoning. Soon Abby finds herself an enemy to many of the doctors in Patience, as well as several people at Colstar, but she finds an ally in Lew Alvarez, another Emergency Room doctor at Patience Regional. Together they work to prove that Colstar has had a Cadmium leak and is responsible for deaths and other issues in Patience.
Yet, somehow, the puzzle never seems to come together for Abby. Too many facts won't link together, and Abby continues to search, putting herself in much danger. And soon, she begins making startling discoveries - ones she never imagined she would find; discoveries for which the price may be her life. In spite of the dangers, her drive to help the people of Patience keeps her working and acting to uncover the truth - but will she be able to prove her case? Or will her enemies discredit her before she can?
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